Unfortunately, there isn't a universally recognized and definitive list of the top 10 Active Pharmaceutical Ingredients (APIs) by production volume.
Reasons are :
Production data confidentiality: Many pharmaceutical companies consider production volume data to be commercially sensitive information, and don't publicly disclose it.
Fluctuations in demand: Demand for specific APIs can fluctuate significantly depending on factors like disease outbreaks, treatment guidelines, and patent expirations.
Ingredient variations: Some APIs have different salt forms or variations that may be tracked separately, making it difficult to determine the volume of the core active ingredient. However, based on industry reports, market research, and news articles, here are some APIs that are likely to be among the top in terms of production volume:
Acetaminophen (Paracetamol): Widely used as a pain reliever and fever reducer.
Ibuprofen: Another common pain reliever and anti-inflammatory medication.
Amoxicillin: A widely prescribed antibiotic belonging to the penicillin group.
Aspirin (Acetylsalicylic Acid): Used for pain relief, fever reduction, and anti-inflammatory purposes.
Omeprazole: A proton-pump inhibitor (PPI) used to reduce stomach acid production.
Simvastatin: A statin medication used to lower cholesterol and reduce the risk of cardiovascular disease.
Metformin: An oral medication used to treat type 2 diabetes.
Atorvastatin: Another statin medication used to lower cholesterol and reduce the risk of cardiovascular disease.
Ciprofloxacin: An antibiotic used to treat a variety of bacterial infections.
Losartan: An angiotensin II receptor blocker (ARB) used to treat high blood pressure and heart failure.